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The TCA cycle

The TCA cycle or Tricarboxylic acid cycle , also known as the Krebs cycle is a compilation of chemical reactions occurring under aerobic conditions to generate energy. The cycle is made up of 8 steps and is catalysed by a number of enzymes. The TCA cycle occurs in the matrix of the mitochondria of eukaryotic cells and in the cytosol of Bacteria which lack mitochondria. The link between glucose and the citric acid cycle is this , when glucose enters glycolysis it is converted to two molecules of pyruvate , these pyruvate molecules are then converted to Acetyl CoA via the link reaction which enters the Kreb’s and cycle continues . The TCA or Kreb’s cycle can be seen below;


Picture taken from

The Medical Biochemistry Page Online